A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of AEB071

Inclusion Criteria: * Male and/or female subjects from 18-55 years of age and in good health as determined by past medical history, physical examination, vital signs, electrocardiogram and laboratory tests at screening. * Female subjects had to either have been surgically sterilized or be postmenopausal. Exclusion Criteria: * Smokers * Use of any prescription drug or over-the-counter medication within 2 weeks prior to dosing, or 2 months for inducers or inhibitors of cytochrome CYP4503A4 (paracetamol acceptable) * Donation or loss of 400 mL or more of blood within 8 weeks prior to dosing * A past medical history of clinically significant ECG abnormalities or a family history of a prolonged QT-interval syndrome * History of History of fainting, hypotension when standing up, arrhythmia, acute or chronic bronchospastic disease * History of clinically significant drug allergy; atopic allergy or a known hypersensitivity to any of the study drugs or drugs similar to the study drugs * Any surgical or medical condition which might significantly alter the absorption, distribution, metabolism or excretion of drugs or which may jeopardize the subject in case of participation in the study * History of immunocompromise (including a positive HIV test result) or drug or alcohol abuse within the 12 months prior to dosing or evidence of such abuse or a current positive Hepatitis B surface antigen (HBsAg) or Hepatitis C test result. Additional protocol-defined inclusion/exclusion criteria may apply