Lamellar Transplant With Lyophilized Corneas

Federal University of São Paulo20 enrolled

Overview

\- The goals of this study are to develop a lyophilization method for anterior lamellar transplants in Brasil and to make a comparative analysis among patients transplanted with lyophilized and optisol corneas

* After the development of a techinique to lyophilize corneas, we randomly assingned 20 patients with keratoconus and visual acuity of \< 20/60, who signed the consent term and divided them into 2 groups. One group was transplanted with lyophilized corneas and the other group with optisol corneas. * Patients are being followed for 6 months with visual acuity, refraction, topography, orbscan, pachmetry, ultrasound biomicroscopy and confocal microscopy. * Results are going to be statistically analysed by SPSS program.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Keratoconus

Interventions

Lamellar transplant with lyophilized corneasPROCEDURE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Keratoconus patient * BCVA \< 20/60 * No systemic diseases * Who signed the inform consent Exclusion Criteria: * BCVA \> 20/60 * Presence of deep opacities * Systemic diseases

Locations (1)

Federal University of Sao Paulo

São Paulo, São Paulo, Brazil

Outcomes

Primary Outcomes

Topography

Orbscan

Pachmetry

Ultrasound Biomicroscopy

Confocal Microscopy

Masked Examiner to evaluate transparency and quality of the transplant

Data from ClinicalTrials.gov

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