Evaluation of Alcon Ladarvision Wavefront-Guided PRK

Inclusion Criteria: * Subjects will be recruited from those active duty soldiers that have requested refractive surgery. Subjects must be eligible for medical care at WRAMC. * Male or female, of any race, and at least 21 years old at the time of the pre-operative examination, and have signed an informed consent. The lower age limit of 21 years is intended to ensure documentation of refractive stability. * Manifest refractive spherical equivalent (MSE) of up to -6 diopters (D) at the spectacle plane with refractive cylinder up to 3.00D. * At least five images must be capturesd in both eyes (dilated) with a pupil size of at least 7mm. * Manifest refraction and LADARWave™ refractions must be within 1.00 D and the CustomCornea® software must allow for treatment with a 6.5mm minor axis and 9mm ablation zone. * Best spectacle corrected visual acuity of 20/20 or better in both eyes. * Demonstrated refractive stability, confirmed by clinical records. Neither the spherical nor the cylindrical portion of the refraction may have changed more than 0.50D during the 12-month period immediately preceding the baseline examination, sa confirmed by clinical records. * Soft contact lens users must have removed their lenses at least 2 weeks before baseline measurements. Hard contact lens users (PMMA or rigid gas permeable lenses) must have removed their lenses at least 4 weeks prior to baseline measurements adn have 2 central Keratometry readings and 2 manifest refractions taken at least 1 week apart that do not differ by more than 0.50D in either meridian; mires should be regular. * Located it the greater Washington DC Area for a 12-month period. * Exhibits strong motivation for attending the follow-up visits. * Consent of the subject's command (active duty) to participate in the study. * Access to transportation to meet follow-up requirements. Exclusion Criteria: * Female subjects who are pregnant, breast feeding or intend to become pregnant during the study. * Concurrent topical or systemic medications that may impair healing, including corticosteriods, antimetabolites, isotretinoin, amiodarone hydrochloride and/ or sumatripin. * Medical condition(s), which, in the judgement of the investigator, may impair healing, including but not limited to: collagen vascular diseases and ocular herpes zoster or simplex. * Active ophthalmic disease, neovascularization of the cornea within 1mm of the intended ablation zone, or clinically significant lens opacity. * Evidence of glaucoma or an intraocular pressure greater than 22mm Hg at baseline. * Evidence of keratoconus, corneal irregularity, or abnormal videokeratography in either eye. * History of recurrent erosions or epithelial baewsment dystrophy. * Patients with known sensitivity or inappropriate responsiveness to any of the medications used in the post-operative course. * Any physical or mental impairment that would preclude participation in any of the examinations.