Myocardial Contrast Echocardiography in Congenital Heart Disease

Insel Gruppe AG, University Hospital Bern45 enrolled

Overview

Patients with congenital heart disease in whom the right ventricle is exposed to pressure or volume overload show progressive systolic dysfunction of the right ventricle, the fact of which conveys substantial morbidity and mortality. The aim of this study is to investigate the myocardial perfusion in these patients by myocardial contrast echocardiography (MCE) in order to determine whether disturbed blood flow plays a role in the development of right ventricular systolic dysfunction.

Study Type

OBSERVATIONAL

Enrollment

Conditions

D-Transposition of Great Arteries Tetralogy of Fallot

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * D-TGA or Fallot-Tetralogy or Healthy person * written informed consent * Age \>= 18 years Exclusion Criteria: * Anaemia * Pregnancy and breast feeding * Diabetes mellitus * Contraindications to stress testing (ergometry or adenosine) * Known adverse reaction or hypersensitivity against V08DA (SonoVue) or its components or against adenosine

Locations (1)

University Hospital Inselspital

Bern, Switzerland

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.