The phase I study will evaluate the safety, efficacy and pharmacokinetics of LBH589B in adult patients with advanced solid tumors or Cutaneous T-cell lymphoma
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
14
Novartis Investigative Site
Tokyo, Japan
To determine the maximum-tolerated dose of LBH589
Time frame: 1st cycle
Safety and tolerability assessed by AEs, SAEs and laboratory values.
Time frame: Every 2 weeks
To characterize the pharmacokinetic (PK) profile of LBH589
Time frame: every 3 cycles
To assess antitumor activity of LBH589
Time frame: every 2 cycles
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