The study is a randomised controlled trial comparing two treatment strategies for patients with moderate functional ischaemic mitral regurgitation undergoing coronary artery bypass grafting (CABG). Patients will be randomised to receive either CABG alone or CABG plus mitral annuloplasty. The objective of the study is to determine if mitral annuloplasty in addition to CABG improves outcome in patients with moderate functional ischaemic mitral regurgitation.
70 patients with moderate functional ischaemic MR who are undergoing CABG will be recruited. Patients will be randomised to undergo either CABG alone or CABG combined with mitral annuloplasty. Patients will be investigated at baseline, 3 months and 1 year after surgery to determine functional capacity, quality of life, and cardiac function.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
73
Patients will receive a mitral annuloplasty ring in addition to coronary artery bypass grafting.
Patients will undergo coronary artery bypass grafting alone.
1st Dept of Cardiothoracic Surgery, Medical University of Silesia
Katowice, Poland
Blackpool Victoria Hospital
Blackpool, Lancashire, United Kingdom
Bristol Heart Institute
Bristol, United Kingdom
Harefield Hospital
Harefield, United Kingdom
Functional capacity
Time frame: 1 year
Left ventricular volumes
Time frame: 1 year
Mitral regurgitation grade
Time frame: 1 year
Neurohormonal levels
Time frame: 1 year
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