Effects of Roaccutane on Ca, P, PTH and Vitamin D Metabolites in the Treatment of Sever Acne

Shahid Beheshti University of Medical Sciences30 enrolled

Overview

serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with isotretinoin for sever acne

few studies has been done of serum levels Ca, P, PTH and vitamin D metabolites in patients receiving isotretinoin .In this study we measured serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with isotretinoin for sever acne in 30 patients . the patients had no kown skeletal, endocrine ,renal and gastrointestinal disorders.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Acne

Interventions

isotretinoin (Roaccutane)DRUG

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * sever acne Exclusion Criteria: * renal disorders * gastrointestinal disorders * skeletal disorders * endocrine disorders * drugs such as glucocorticoids , thiazide diuretics, mineral multivitamins, anti acids, tetracyclines

Locations (1)

Shaheed Beheshti Medical University, Skin research center

Tehran, Iran

Outcomes

Primary Outcomes

serum levels of Ca, P, PTH and vitamin D metabolites and lateral chest x-ray before the treatment

Secondary Outcomes

serum levels of Ca, P, PTH and vitamin D metabolites and lateral chest x-ray after the treatment

Data from ClinicalTrials.gov

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