This is a randomized, parallel, single-blinded multi-center study. The objective is to compare the long term clinical outcomes among the site of atrial pacing and to compare the long term effect of the atrial fibrillation (AF) Suppression algorithm.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
385
Pacemaker implantation with RA lead placed in low atrial septal position
Pacemaker implantation with RA lead placed in low atrial septal position
Pacemaker implantation with RA lead placed in right atrial appendage position
Queen Mary Hospital, The University Hospital of Hong Kong
Hong Kong, Hong Kong
Persistent AF and chronic AF
Time frame: 2 years
Device diagnostic data: number of atrial high rate episode, mode switch episode and AF burden
Time frame: 2 years
Number of cardioversions
Time frame: 2 years
Safety and efficacy of low septal pacing
Time frame: 2 years
Echocardiogram (Echo) parameters include left ventricular ejection fraction (LVEF) and diastolic index using Doppler Echo
Time frame: 2 years
Quality-of-life questionnaire: Short Form-36 (SF-36)
Time frame: 2 years
Major cardiovascular events: heart failure, stroke, hospitalization, and cardiovascular mortality
Time frame: 2 years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Pacemaker implantation with RA lead placed in right atrial appendage position