Hypothesis: We hypothesize that resuscitation regimens which minimize the total volume of resuscitation fluid, while restoring organ perfusion, will lead to lower morbidity and mortality in critically ill patients following trauma.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
81
no vasopressin added to bolus or 5 hour continuous infusion
vasopressin bolus 4 units followed by continuous infusion 2.4units/hr for 5 hours
University of Texas Health Science Center at San Antonio
San Antonio, Texas, United States
The Primary Endpoint of This Study Will be Day 30 Mortality.
Survival of a traumatic injury subject to at least 30 days after admission to the emergency room.
Time frame: 30 days
Level of Vasopressin After Trauma.
Level of vasopressin 12 hours after infusion was measured for all subjects in vasopressin arm
Time frame: 12 hours
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