To compare the effects of taranabant versus placebo on weight regain and weight maintenance after low calorie diet-induced weight loss in obese patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
1,000
taranabant 0.5 mg capsule, 1 mg capsule, 2 mg capsule once daily. Treatment for 52 weeks.
Placebo capsules once daily. Treatment for 52 weeks
Body weight at 52 weeks, safety and tolerability.
Time frame: 52 weeks
Body weight, biochemical markers, blood pressure, waist circumference and patient reported outcomes at 52 weeks.
Time frame: 52 weeks
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