The long-term goal of this project is to develop a non-invasive, noise-based technique for enhancing somatosensation and thereby improving balance control in elderly fallers and older adults with somatosensory deficits.
Previous studies have shown that sub-sensory mechanical noise (i.e., random vibration with a small intensity) can enhance somatosensory function in healthy individuals and older adults with somatosensory deficits. Moreover, the postural sway of both healthy young and healthy elderly individuals during quiet standing can be significantly reduced by applying sub-sensory mechanical noise to the feet using vibrating shoe insoles. The specific aims of this project are to determine the effects of noise-enhanced somatosensation at the feet on balance performance in elderly individuals with somatosensory deficits and/or recurrent falls, and to assess whether adaptation occurs in noise-enhanced balance control in these individuals. To accomplish these aims, quiet-standing and dynamic posture studies and clinical balance assessments will be conducted on elderly individuals with somatosensory deficits and elderly individuals with recurrent falls (two or more falls over a 12-month period). This project could lead to the development of a novel bioengineering technique for improving balance control in older adults and patients with somatosensory deficits. The work could thus serve to reduce the frequency, morbidity and cost of falling, and assist aged individuals in achieving maximal independence in activities of daily living and mobility. Two groups of participants will be recruited from the RNH Epidemiology Core: 85 elderly individuals with somatosensory deficits, and 85 elderly individuals with recurrent falls. The study consists of three visits--a one-hour neurological exam, and two 6-hour laboratory testing sessions scheduled one week apart.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
170
Participants wear vibrating sandals for 3 trials of 6 minutes, during a single lab visit. The sandal vibration is on during either first or second 3 minutes of the 6 minute trial, as they walk. Also, participants wear the sandals for 2 hours while sitting, with vibrations on for one visit and off for the other.
Applied Biodynamics Laboratory, Boston University
Boston, Massachusetts, United States
RECRUITINGArea ellipse of sway
Time frame: Three 6-minute trials in one visit, repeated one week later
Berg Functional Balance Scales
Time frame: Three 6-minute trials in one visit, repeated one week later
Timed Up and Go (TUG)Test
Time frame: Three 6-minute trials in one visit, repeated one week later
Timed one-legged stance test
Time frame: Three 6-minute trials in one visit, repeated one week later
Gait timing variability
Time frame: Three 6-minute trials in one visit, repeated one week later
Changes in: stabilogram-diffusion analysis (SDA)
Time frame: Three 6-minute trials in one visit, repeated one week later
Neurological risk factors related to falls
Time frame: Three 6-minute trials in one visit, repeated one week later
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.