Multimodal Intervention in Allogeneic Stem Cell Transplantation

Rigshospitalet, Denmark42 enrolled

Overview

Objective: To evaluate the feasibility and safety of a 4-6 weeks exercise - psycho-educational intervention in patients undergoing allogeneic stem cell transplantation (allo-HCST). The intervention included structured and supervised exercise, relaxation and psycho-educational components. It was hypothesized that the intervention would minimize loss of physical capacity during hospitalization.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Allogeneic Stem Cell Transplantation Leukemia

Interventions

Multimodal exercise and psychosocial programBEHAVIORAL

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 18-65 yrs * patients undergoing allogeneic stem cell transplantation Exclusion Criteria: * recent cardiovascular or pulmonary disease * abnormal EKG * psychiatric disorder * motor function, musculoskeletal or neurological disturbances * bony metastasis

Locations (1)

Copenhagen University Hospital

Copenhagen, Denmark

Outcomes

Primary Outcomes

Physical capacity VO2 max, muscle strength (1RM, Isometric), stair test

Time frame: Baseline, post

Secondary Outcomes

quality of life indices

Time frame: baseline, post, 3 and 6 months

FACT-An, EORTC, HADS, Mini-Mac, Symptom Assessment form

Time frame: baseline, post, 3 and 6 months

Data from ClinicalTrials.gov

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