Long-Term IOP Fluctuation and VF Progression After Triple Procedure

Yonsei University300 enrolled

Overview

Long-term intraocular pressure (IOP) fluctuation may be significantly associated with the progression of glaucomatous visual field loss, even in patients kept always low IOP after triple procedure, an effective approach for patients with coexisting glaucoma and visually significant cataracts.

Previous studies reported that lowering intraocular pressure (IOP) slowed the advancement of visual field damage in glaucoma patients. However, even if the IOP can been substantially lowered, reduction of mean and peak IOP does not always prevent visual field progression.We believe that the long-term IOP fluctuation may play a significant role in visual field deterioration in those patients.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Glaucoma Filtering Surgery Intraocular Pressure

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: 1. Underwent triple procedure 2. At leas 3 years of follow-up after surgery 3. IOP \<18mmHg at each postoperative visit 4. A minimum of 5 visual field examinations 5. A reference visual field defect score of 16 or less 6. Good reliability indices of visual field Exclusion Criteria: 1. Any other significant ocular diseases or intraocular surgical histories, 2. Diseases that may affect visual field or diabetes

Locations (1)

Yonsei University College of Medicine

Seoul, South Korea

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.