Effect of Nutritional Intervention on the Lipid Profile of HIV-Positive Patients Who Start HAART: a Randomized Trial

Hospital de Clinicas de Porto Alegre80 enrolled

Overview

Highly active antiretroviral therapy (HAART) in HIV-positive patients is associated with the development of dyslipidemia, a risk factor for cardiovascular events. The objective of this study was to evaluate the effect of dietary intervention in individuals who start HAART.

Adult patients prescribed to HAART that met the exclusion criteria were consecutively enrolled in a randomized trial: * control (receiving general guidelines on dietary education) * intervention (receiving general guidelines on dietary education and nutritional follow-up every 3 months)

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

HIV Infections

Interventions

NutritionalBEHAVIORAL

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * HIV-positive individuals naive to HAART, with clinical indication to start therapy Exclusion Criteria: * Diabetes Mellitus * Pregnancy * Active opportunistic disease * Any mental deficiency * Use of lipid profile influencing drugs * Use of illicit drugs

Locations (1)

Hospital de Clínicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil

Outcomes

Primary Outcomes

Total cholesterol and of triglycerides levels

Secondary Outcomes

HDL-cholesterol, LDL-cholesterol, weight, waist to hip ratio

Data from ClinicalTrials.gov

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