Vasoactive Hormones and Oxygen Saturation During Apneic Events in Patients With Obstructive Sleep Apnea

Regional Hospital Holstebro40 enrolled

Overview

The mechanisms involved in development and maintenance of hypertension in obstructive sleep apnea are not clarified. We hypothesize that patients with obstructive sleep apnea have an abnormal level of some vasoactive hormones during apneic events during sleep.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Obstructive Sleep Apnea

Eligibility

Sex: ALLMin age: 20 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Patients with Obstructive sleep apnea Inclusion Criteria: * Severe obstructive sleep apnea (apnea-hypopnea index \> 30) Exclusion Criteria: * Drug or alcohol abuse * Pregnancy * History or clinical signs of disease in the heart, lungs, brain, liver, kidneys or endocrine organs * Diabetes Healthy Controls Inclusion Criteria: * Apnea-hypopnea index \< 10 Exclusion criteria: * Drug or alcohol abuse * Pregnancy * History or clinical signs of disease in the heart, lungs, brain, liver, kidneys or endocrine organs * Diabetes

Locations (1)

Department of Medical Research, Holstebro Hospital

Holstebro, Denmark

Data from ClinicalTrials.gov

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