Ph1 Lobeline Interaction Study - 1

Inclusion Criteria: * Be between the ages of 18 and 45 years of age * Be in general good health with a history of methamphetamine (MA) abuse (but not dependence) * If female and of child bearing potential, agrees to use birth control * Be able to understand and provide written informed consent * Have a body mass index between 18 and 30 * Have reported use of (MA) during the past three months without experiencing adverse consequence plus a life time MA or amphetamine use history of at least four occasions of use * Have a negative drug test (barbiturates, benzodiazepines, amphetamines, opiates, cocaine, cannabinoids, ethanol) at screening and at the time of admission Exclusion Criteria: * Please contact site for details