Evaluate the Effects of Patupilone on the Pharmacokinetics of Midazolam and Omeprazole in Patients With Advanced Malignancies (Extension)

Inclusion criteria: * Male or female patients 18 years or older * Histologically documented advanced solid tumor, who have failed standard systemic therapy, or for whom standard systemic therapy does not exist * Completed the Core study * Completed all sampling in the core and not dose reduced Patients with adequate hematologic parameters Exclusion criteria: * Female patients who are pregnant or breast-feeding. * Patients with a severe and/or uncontrolled medical disease * Patients with a known diagnosis of human immunodeficiency virus (HIV) infection * Patients having received an investigational agent within 30 days prior to study entry Other protocol-defined inclusion/exclusion criteria may apply