Caesarean and Corticotherapy

University Hospital, Strasbourg, France200 enrolled

Overview

Comparison of two randomized group : * caesarean section planned at 38 weeks after 2 antenatal injections of 12 mg of betamethasone 48 h before. * caesarean section planned at 39 weeks without corticosteroid. The aim is to demonstrate that programming caesarean section at 38 weeks of pregnancy, after antenatal corticosteroid, allows to avoid caesarean section in emergency (because of a labour before 39 weeks), without increasing the neonatal respiratory distress rate.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

200

Conditions

Neonatal Distress

Interventions

betamethasoneDRUG

2x12 mg betamethazone c-section at 38 weeks

placeboOTHER

c-section at 39 weeks

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * woman who needs elective caesarean section Exclusion Criteria: * multiple pregnancy * toxaemia * rhesus immunization * fetal infection * maternal gastro-duodenal ulcer * mother HIV+ * prior injection of corticosteroid during the pregnancy

Locations (5)

Le Parc Centre pour la Mère et l'Enfant

Colmar, France

Centre Hospitalier de Haguenau

Haguenau, France

Hôpital de Hasenrain

Mulhouse, France

Cmco-Sihcus

Schiltigheim, France

Hôpital de Hautepierre

Outcomes

Primary Outcomes

Neonatal respiratory distress

Time frame: 15 days

Data from ClinicalTrials.gov

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