Combined Effects of Nutritional and Exercise Countermeasures

Inclusion Criteria: * 18-50 years of age * Availability of transport and ability to report to Research Center at appointed times Exclusion Criteria: * Subjects with limiting or unstable angina or a cardiology confirmed ECG which demonstrates cardiac abnormalities such as \> 0.2 mV horizontal or downsloping ST segment depression, frequent arrhythmia's (\>10 PVC/min), or valvular disease. * Subjects with vascular disease as determined by a combination of risk factors of peripheral atherosclerosis, namely hypertension, obesity, diabetes, hypercholesterolemia and/or evidence of venous or arterial insufficiency upon palpitation of femoral, popliteal, and pedal arteries. * Any history of hypo- or hyper-coagulation disorders including subjects taking Coumadin or with a history of DVT or PE at any point in their lifetime. * Any subject that has a chronically elevated systolic pressure \>170 or a diastolic blood pressure \> 100 will be excluded. Subjects may be included if they are taking blood pressure medication and have a blood pressure below these criteria. * Any subject with an uncontrolled metabolic disease including liver or renal disease. * Fasting blood glucose of \>126 mg/dl on two separate occasions * Presence of acute illness or metabolically unstable chronic illness. * Any subject currently on weight-loss diet. * Inability to abstain from smoking for duration of study. * Recent ingestion of anabolic steroids (within 6 months). * Subjects with atrial fibrillation, history of syncope, angina or congestive heart failure. * Subjects with a recently (6 months) treated cancer other than Basal Cell Carcinoma. * Pregnancy/lactation. * Any other condition or event considered exclusionary by the PI and covering faculty