Study of the Natural Variation in Strokevolume

Rigshospitalet, Denmark20 enrolled

Overview

We would like to investigate the natural variation in the strokevolume of the heart. At the same time we would like to find out the minimal number of heart cycles necessary to discover a 10% increase in strokevolume, after a fluid bolus of 200ml Voluven, when using Esophageal Doppler.

We would like to investigate the natural variation in the strokevolume(SV) of the heart. At the same time we would like to find out the minimal number of heart cycles necessary to discover a 10% increase in SV, after a fluid bolus of 200ml Voluven, when using Esophageal Doppler. Also we will compare the variation in SV both before and after the patients have been fluid optimized, using an algorithm of 10% increase in SV in order to receive another fluid bolus. The equipment used, will be the CardioQ from Deltex medical.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Stroke Volume Variation

Interventions

Esophagus Doppler monitoringPROCEDURE

Fluid optimizationPROCEDURE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Planned abdominal surgery Exclusion Criteria: * Oesophageal pathology, * Age \>90 yr or \<18 yr, * Alcohol abuse, * Aneurism in thoracic aorta

Locations (1)

Rigshospitalet

Copenhagen, Region Sjælland, Denmark

Outcomes

Primary Outcomes

Strokevolume variation before fluid optimization

Strokevolume variation after fluid optimization

Number of cycles needed in order to detect a 10% strokevolume increase after fluid bolus of 200ml Voluven.

Data from ClinicalTrials.gov

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