Safety and Efficacy of Prulifloxacin vs Placebo in Treatment of Acute Gastroenteritis in Adult Travelers

Inclusion Criteria: * Diagnosis of acute bacterial gastroenteritis * Traveler from an industrialized country * Capable of giving Informed Consent Exclusion Criteria: * Fever (\>100.3 degrees) * Pregnant or Breast Feeding or Not using adequate birth control * Known or Suspected (co-)Infection with non-bacterial pathogen * Symptoms of acute gastroenteritis of \>72 hours duration * Bloody Diarrhea * Concomitant antibacterial with activity against enteric bacterial pathogens * History of IBD * Unable/Unwilling to comply with study protocol * Greater than two doses of an antidiarrheal medication within 24 hours * \> 2 doses of anti-diarrheal medication within 24 hours * Antimicrobial treatment within 30 days