Efficacy and Safety Study of Polyphenon E to Treat External Genital Warts

Inclusion Criteria: * Age \>= 18 years at the time of enrollment * Clinical diagnosis of external genital warts (located genital, inguinal, perineal or perianal) * At least 2, but no more than 30 external genital warts * A total wart area between 12 and 600mm² * Negative pregnancy test and willingness to use effective contraception (for women of child-bearing potential) * For partners of male patients who are of child-bearing potential: use of effective contraception during the treatment period * Written informed consent * Ability to comply with the requirements of the study Exclusion Criteria: * Participation in an investigational trail within 30 days prior to enrollment * Previous participation in a trial investigating Polyphenon E in the treatment of external genital warts * Treatment of external genital warts within 30 days prior to enrollment and for the whole study duration * Systemic intake of virostatics within 30 days prior to enrollment and for the whole study duration * Systemic intake of immunosuppressive or immunomodulatory medication within 30 days prior to enrollment and for the whole study duration * Current infection with Herpes genitalis or history of Herpes genitalis infection within the last 3 month * Any current and/or recurrent pathologically relevant genital infections other than genital warts * Current known acute or chronic infection with HBV or HCV * Known HIV infection * Any current uncontrolled infection * Organ allograft * For female patients: pregnancy or lactation * Known allergies against any of the ingredients of the treatments * Any chronic or acute skin condition susceptible of interfering with the evaluation of the drug effect * Any chronic condition susceptible, in the opinion of the investigator, of interfering with the conduct of the study * Internal (vaginal or rectal) warts requiring treatment