The purpose of this study is to compared between conventional pterygium excision and AMT transplantation with suture and with fibrin glue.
There are few studies about use of fibrin glue in pterygium surgery with conjunctival auto-graft with promising outcome. Less recurrent rate, less discomfort and halve surgical time were reported. Up to our knowledge,there is no report of fibrin glue in pterygium excision with amniotic membrane transplantation(AMT). There is conventional technique to use AMT in King Chulalongkorn Memorial Hospital because some benefits over conjunctival auto-graft e.g. * Preserve healthy superior conjunctiva for future glaucoma filtering surgery * Can use in big or 2-headed pterygium * Not contract as conjunctival graft esp. in case of fibrin glue * Potential easier to use with fibrin glue * Available from Thai Red Cross Eye Bank Comparison(s): amniotic membrane transplantation using fibrin glue compare to suture after pterygium excision.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
32
After pterygium excision, amniotic membrane was shaped and attached to bare scleral area using fibrin glue (Quixil®) in 16 eyes of 16 patients of FG group and continuous suture with nylon 10-0 in 16 eyes of 16 patients of SU group.
Department of Ophthalmology, King Chulalongkorn Memorial hospital
Bangkok, Thailand
Pain and discomfort during and after surgery using visual analog scale
Time frame: during surgery and after surgery up to 30 days
Surgical time
Time frame: start and to the end of surgery
Healing of epithelial defect on cornea and AMT
Time frame: until 30 days
Postoperative inflammation
Time frame: up to 30 days
Complications e.g. Recurrent, graft loss/dehiscent, re-operation
Time frame: until last follow up
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