This is a double-blind, placebo-controlled study to assess the effectiveness of BiosLife in lowering serum LDL cholesterol and raising HDL cholesterol. BiosLife is a natural supplement (mixed in water and taken twice daily) which contains guar gum and other natural soluble fibers, phytosterols, policosanol, and a proprietary chrysanthemum extract. Approximately 100 subjects with baseline LDL cholesterol of 110-190 mg/dL will be randomized in a 2:1 ratio to BiosLife or a look-alike placebo. Changes in lipids from baseline will be assessed at 6 weeks and 12 weeks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
100
Cardiovascular Genetics, University of Utah, 420 Chipeta Way, Room 1160
Salt Lake City, Utah, United States
LDL cholesterol
Time frame: 12 weeks
HDL cholesterol
Time frame: 12 weeks
triglycerides
Time frame: 12 weeks
LDL particle number
Time frame: 12 weeks
LDL particle size distribution
Time frame: 12 weeks
HDL particle number
Time frame: 12 weeks
HDL particle size distribution
Time frame: 12 weeks
VLDL particle number
Time frame: 12 weeks
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