A Study to Compare the Efficacy and Safety of FK506MR vs Prograf® in Patients Undergoing Liver Transplantation

Inclusion Criteria: * Written informed consent with the date of the patient must be obtained. * Patient between 18-70 years of age receiving the primary liver. * Female patients must have a negative pregnancy test prior to the enrolment. * Female patients of child bearing potential must agree to practice effective birth control during the study Exclusion Criteria: * Liver re-transplantation patients or received an organ transplantation other than a liver. * Living-related liver transplantation patient. * Patient has received an AB0 incompatible donor liver. * Patient who needs antibody induction therapy. * Patient with sever infection requiring treatment. * Patient has any history of severe cardiovascular, respiratory disease; or history of malignancy, liver cancer not included.