Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-611)

Inclusion Criteria: (All questions must be answered YES) * Has the patient given written informed consent? * Is the patient at least 18 years old? * Does the patient have transitional cell carcinoma of the bladder with clinically apparent stage Ta, grade G1-G2? * If the patient is a female of childbearing potential, is she using an acceptable/effective method of contraception? * If the patient is a female of childbearing potential, has she had a negative serum pregnancy test within the past 14 days? * Is the patient willing and able to abide by the protocol? Exclusion Criteria: (All questions must be answered NO) * Does the patient have more than 4 bladder tumors? * Does any single bladder tumor exceed 3.5 cm in diameter? * Does the patient have a single, primary (no previous diagnosis of TCC) bladder tumor \<0.5 cm? * Has the patient ever received Apaziquone? * Does the patient have, or has the patient ever had, any bladder tumor known to be other than stage Ta or grade G1 or G2 (low grade \[WHO/ISUP classification\])? * Does the patient have, or has the patient ever had any bladder tumor with histology other than transitional cell carcinoma? * Does the patient have, or has the patient ever had, carcinoma in situ (CIS)? * Does the patient have an active urinary tract infection? * Does the patient have a bleeding disorder or a screening platelet count \< 100 x 10\^9/L? * Does the patient have any unstable medical condition that would make it unsafe for him/her to undergo TURBT under general or spinal anesthesia? * Does the patient have a screening hemoglobin \< 10 mg/dL, a screening absolute neutrophil count \< 1.5 x 10\^9/L or a screening creatinine \> 2 mg/dL? * Does the patient have a known immunodeficiency disorder? * Has the patient received any investigational treatment within the past 30 days? * Is the patient breast feeding? * Does the patient have a history of interstitial cystitis? * Does the patient have a history of allergy to red color food dye? * Has the patient had transitional cell carcinoma of the bladder within the past 4 months?