Meropenem Versus Meropenem Plus Glycopeptide in Patients With Febrile Neutropenia After Allogenic Blood Stem Cell Transplantation

Inclusion Criteria: * Age \> 18 years * Patients submitted to allogenic transplant * Neutropenia: neutrophils account \< 500/mm3 or neutrophils account \< 1000/mm3 with prevision to decrease until 500/mm3 at the next 24-48 h * Signs and symptoms to infection * Fever: Temperature\> 38,3 ºC registered one time, or 38 ºC en two times separated 60 minutes in a period of 12 h. Exclusion Criteria: * Medical history of meropenem or glycopeptides hypersensitivity * Renal failure or creatinine in serum \> 2,25 mg/dl or creatinine clearance \< 40 ml * Liver insufficiency * Childbearing potential or breast feeding period * Contraindications to meropenem, vancomycin or teicoplanin