A study to determine the ability of different doses of PF-610,355 to open the airways in asthmatic patients by comparison with placebo and a marketed drug that also opens the airways in asthmatic patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
42
Pfizer Investigational Site
Berlin, Germany
Pfizer Investigational Site
Großhansdorf, Germany
Pfizer Investigational Site
Wiesbaden, Germany
Pfizer Investigational Site
Gothenburg, Sweden
Peak and Trough (24 hour post dose) FEV1.
Peak and trough (24 hour post dose) PEFR
FEV1 and PEFR measurements to 32 hours post dose.
Pharmacokinetics of PF-610,355 and salmeterol
Safety/Pharmacodynamic end points - pulse rate, blood pressure, QTcF, plasma potassium, blood glucose and AEs.
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Pfizer Investigational Site
Lund, Sweden
Pfizer Investigational Site
Manchester, United Kingdom