EXTEND III - Efficacy and Safety of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)

Inclusion Criteria: * Male or female Asian patients 50 years of age or greater. * Patients with primary or recurrent subfoveal CNV secondary to AMD, including those with predominantly classic, minimally classic or active occult lesions with no classic component. * Patients who have a BCVA score between 73 and 24 letters (approximately 20/40 to 20/320 Snellen equivalent), inclusively, in the study eye. * Total area of CNV (including both classic and occult components) encompassed within the lesion must be \>= 50% of the total lesion area * Total lesion area must be \<= 12 disc areas Exclusion Criteria: * Patients who have in the fellow eye a Snellen equivalent below 20/200 * Presence of angioid streaks, presumed ocular histoplasmosis syndrome, myopia (exceeding -8 diopters), or CNV secondary to causes other than AMD in the study eye * Subfoveal fibrosis or atrophy in the study eye * Total area of CNV (including both classic and occult components) encompassed within the lesion must be \>= 50% of the total lesion area * Total lesion area must be \<= 12 disc areas * Vitreous hemorrhage, retinal tear or history of rhegmatogenous retinal detachment or macular hole (Stage 3 or 4) in the study eye. * Active, or history of, ocular inflammation or infection in the study eye within the last 30 days prior to screening. * Uncontrolled glaucoma in the study eye * Treatment in the study eye with verteporfin, external-beam radiation therapy, subfoveal focal laser photocoagulation, vitrectomy, submacular surgery, or transpupillary thermotherapy within 30 days prior to screening * Previous treatment with anti-angiogenic drugs (pegaptanib, ranibizumab, bevacizumab, anecortave acetate, corticosteroids, protein kinase C inhibitors, squalamine, siRNA, VEGF-Trap etc.) for neovascular AMD in the study eye. Treatment of the fellow eye is permitted if administered \> 30 days before screening. * History of intraocular surgery in the study eye including pars plana vitrectomy, except for uncomplicated cataract surgery more than 60 days prior to screening * History of YAG laser posterior capsulotomy in the study eye within 30 days prior to screening