The purpose of this study is to assess the efficacy and safety of 8 weeks of daily treatment with Ilaprazole (5, 20 and 40 mg), once daily (QD), compared to lansoprazole 30 mg in healing subjects with endoscopically proven erosive esophagitis.
This 8 week study will be conducted by approximately 160 investigators in the United States. During this study, esophagitis healing will be evaluated by endoscopy, heartburn and other symptom relief will be evaluated by questionnaire and study drug levels will be measured.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
831
Ilaprazole 5 mg, capsules, orally, once daily for up to 8 weeks.
Ilaprazole 20 mg, capsules, orally, once daily for up to 8 weeks.
Ilaprazole 40 mg, capsules, orally, once daily for up to 8 weeks.
The crude healing rate of Erosive Esophagitis at week 4 of treatment as assessed by endoscopy.
Time frame: Week 4
The crude healing rate of Erosive Esophagitis at week 8 of treatment as assessed by endoscopy.
Time frame: Week 8
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Lansoprazole 30 mg, capsules, orally, once daily for up to 8 weeks.
Unnamed facility
Hueytown, Alabama, United States
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Huntsville, Alabama, United States
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Chandler, Arizona, United States
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Phoenix, Arizona, United States
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Tempe, Arizona, United States
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Tucson, Arizona, United States
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Sherwood, Arkansas, United States
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Anaheim, California, United States
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Cypress, California, United States
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Encinitas, California, United States
...and 84 more locations