Previous studies have shown that alcohol significantly impairs driving performance. Acute alcohol administration also has a detrimental effect on secondary task performance during dual-tasks. The present study will investigate the effects of five different dosages of ethanol (0,0.2, 0,5, 0,8 and 1,0 % BAC) on performance in a driving simulator. Steering performance and brain activity will be recorded in both single- and dual-task conditions.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
32
alcohol(0.02%, 0.05%, 0.08% and 0.10%) and placebo
Utrecht Institute for Pharmaceutical Sciences
Utrecht, Utrecht, Netherlands
Primary parameter of the steering simulator is the standard deviation of the car from the center of the road (steering error).
Time frame: 5 testdays
Reaction speed after hearing the deviant target tone. Brain activity: ERPs of interest are the mismatch negativity (MMN), P3a, P3b, and reorienting negativity (RON)
Time frame: 5 testdays
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