Pharmacodynamic Study of the Effect of INCB013739 on Insulin Sensitivity in Obese, Type 2 Diabetic Subjects

Inclusion Criteria: 1. Have an established diagnosis of Type 2 Diabetes as determined by the investigator. 2. Females will be postmenopausal for at least 1 year with documented FSH \> 30 IU/L. Exclusion Criteria: 1. Hypertriglyceridemia \> 500 mg/dL at screening. 2. BMI \> 40 kg/m2. 3. Receiving thiazolidinediones, insulin, or exenatide within the 3 months prior to screening. 4. History or clinical manifestations of Addison's disease, Cushing's Syndrome, or other disorders involving glucocorticoids or mineralocorticoids. 5. Current treatment or treatment within 30 days or five half-lives (whichever is longer) prior to the first dose of study medication with another investigational medication or current enrollment in another investigational protocol.