The Biology of Claudin 3 in Primary Human Mammary Epithelial Cell Culture

Hackensack Meridian Health13 enrolled

Overview

The objective of the present study is to determine whether or not primary human mammary epithelial cells are competent for use in molecular studies of transepithelial electrophysiology focusing on the function of the tight junction protein claudin 3. Human breast Tissue will be removed from mastectomy specimens and used as a source to generate epithelial cells for study.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Breast Cancer

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * Subjects of this pilot study are limited to those female patients who are undergoing therapeutic or prophylactic mastectomy procedures conducted by the department of Surgery at HUMC. Exclusion Criteria: * From within this population, no exclusion criteria shall be applied based on age, race, ethnicity, gender, HIV status, or menopause.

Locations (1)

Hackensack Univeristy Medical Center

Hackensack, New Jersey, United States

Outcomes

Primary Outcomes

Cell line data study

Time frame: one year

Data from ClinicalTrials.gov

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