Safety & Performance Randomized Study of the CiTop™ Guidewire for Peripheral CTO

Clinical Inclusion Criteria: * Patient with symptomatic peripheral vascular disease, intermittent claudication less than 30 meters, rest pain or tissue ischemia.(Fontain grade 3-4) * Critical limb Ischemia * The patient has Chronic Total Occlusion in limb arteries, aged at least 3 months. * Patient has chronic total occlusion (CTO) that is: * Documented angiographically, by the investigator or co-investigator. * CTO was defined as an obstruction of a main peripheral artery with no luminal continuity and with TIMI (Thrombolysis In Myocardial Infraction) flow grade of 0 or 1. * CTO location suitable for endovascular treatment (not in parallel location with the hip or knee joints). * Lesion ≤ 8cm in length * Lesion located in a segment with diameter more than 1.5 mm * Adequate compliance with follow-up and/or repeat angiography * No Contra-indication to treatment with aspirin or ticlopidine or clopidogrel and/or Heparin * Visible entry point of target lesion * NO cancer or other life threatening diseases or conditions * NO diagnosis or suspected renal failure (2 x ULN of creatinine) * Not suspected intolerance of the contrast agent * NO Drug abuse or alcoholism * Patients is NOT under custodial care * Women with childbearing potential are NOT pregnant (positive pregnancy test at the time of procedure).