Multi-Centre Trial Comparing Three Artemisinin-Based Combination Treatments on P. Falciparum Malaria

Inclusion Criteria: * age at least 6 months, * weight at least 5 kg, * residing in one of the four countries (Mali, Cameroon, Sudan, Rwanda), * able to receive oral treatment, * having an axillary body temperature of more than 37,5 degrees Celsius or history of fever within the proceeding 24 hours, * suffering from a mono specific P. falciparum infection with a parasite density between 2000 and 200000 asexual forms per micro litre of blood. Exclusion Criteria: * presence of severe or complicated malaria (WHO 2000), * severe concomitant pathology or one that needs a medical follow-up incompatible with the study, * allergic to one of the drugs involved in this study, * pregnant (reported pregnancy, detected clinically or with the β HCG test), * use of one of the anti-malaria drugs involved in this study during 28 days preceding inclusion.