The maximal walking distance (MWD) performed on treadmill (TT) remains the gold standard in estimating the walking capacity of patients suffering from peripheral arterial disease (PAD) with intermittent claudication, although treadmills are not accessible to most physicians. We hypothesized that global positioning system (GPS) recordings could monitor community-based outdoor walking and provide valid information on walking capacity in PAD patients.
The study has two main objectives, conducted together. Each objective include several phases. Objective 1: technical validation of GPS measurements in healthy subjects. phase 1: technical validation of a GPS device to study outdoor walking (completed). phase 2: comparison and use of various GPS devices (intra- and inter-GPS variability) in the study outdoor walking (on-going). phase 3: study of several factors that could influence accuracy of GPS measurements as walking speed, environment, sampling frequency and others technical features as the WAAS/EGNOS function (on-going). Objective 2: Application in PAD patients to study walking capacity under free-living conditions phase 1: comparison of GPS measurements (maximal walking distance) with the gold standard treadmill measurement of maximal walking distance (completed). phase 2: analysis of the variability of the walking capacity under free-living conditions from GPS measurements (completed). phase 3: study of reliability and sensibility (effect of treatment) of GPS measurements (on-going). phase 4: study of the relationship between laboratory measurements of walking capacity and GPS-derived parameters.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
140
Analyse the clinical change after surgery from GPS measurements and compare it with laboratory measurement.
Centre hospitalier universitaire
Angers, France
Validate the ability of GPS to detect walking and resting bouts and to accurately estimate walking speed and distance in normal subjects.
Time frame: 2 years
Measurement of maximal walking distance using GPS and comparison with treadmill measurement in PAD patients.
Time frame: 2 years
Determine the variability of the walking capacity and its potential determinants in PAD patients.
Time frame: 3 years
Analyse the reliability and sensibility of GPS measurements of the walking capacity in PAD patients.
Time frame: 4 years
Analyse potential factors that could affect the accuracy of GPS measurements
Time frame: 4 years
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