Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation

Inclusion Criteria: * Infection or suspected infection resulting in sepsis and DIC Exclusion Criteria: * Unable to provide informed consent, or lack of consent from an acceptable surrogate * Subjects \< 18 years of age * Known conditions that could confound the diagnosis of DIC due to sepsis * Known conditions that increase the risk of bleeding * Known medical condition associated with a hypercoagulable state * Known or suspected severe liver disease * History of solid organ (excluding uncomplicated kidney), bone marrow or stem cell transplantation * Renal failure