Fluid Management for Cesarean Section

Nanjing Medical University850 enrolled

Overview

Cesarean section-associated hypotension is one of the pivotal factors to influence the Apgar Score of children and related with the stable hemostasis during the whole process of labor. How to keep circulation in a consistent stability is yet to be known. The investigators hypothesized that different fluids, crystalloids or colloids, can produced varying effects in keeping the physiological environment of labor from significant fluctuating.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

850

Conditions

Cesarean Section

Interventions

Ringer's LactateOTHER

Ringer's Lactate was used 15min before operation

6% StarchOTHER

6% Starch was used 15min before operation

Eligibility

Sex: FEMALEMin age: 21 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 21-40 yr * First time of delivery * ASA status I-II * No premature * No genetic and infectious diseases * Chinese Exclusion Criteria: * \< 21 yr * \> 40 yr * Subjects with cardiac and pulmonary disorders * Dislocation of placenta * Pregnant hypertension * Allergy to local anesthetics * Unwilling to cooperation * Need intraoperative administration of vascular active agents * With significant delivery side effects

Locations (1)

Nanjing Maternal and Child Care Hospital

Nanjing, Jiangsu, China

Outcomes

Primary Outcomes

Total volume of colloid Total volume of crystalloid Total fluid volume

Time frame: 6 months

Secondary Outcomes

Percentage reduction in hematocrit, Days in hospital

Time frame: 6 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.