Blood Endothelium Progenitor Cells and Dendritic Cells as Predictive Biomarkers of In-stent Restenosis

Inclusion Criteria: * Age\>18 years old * Scheduled for PCI * Candidate for CABG if necessary * Clinical evidence of ischemic heart disease and/or abnormal functional study * New native coronary artery lesion \>50%-\<100% stenosis * Lesion length\<30 mm, treatment with a single bare metal stent planned * Reference diameter 2.5-3.5 mm * Informed consent explained, red, understood and signed by the patient Exclusion Criteria: * Pregnancy, birth or lactation period \<6 months ago * Women of childbearing age who do not intend to use accepted anticonceptive measures or who wish to get pregnant * Left ventricular ejection fraction \<30% * Acute myocardial infarction (ST-elevation, Q-wave evolution or CK-MB \>2x upper limit of normal)in the past month * Contra-indication to PCI * Diabetes mellitus * Planned drug eluting stent implantation * Total occlusion (TIMI 0 or 1) * Ostial localisation (\<3.0 mm of the coronary ostium) of the lesion * Bifurcational lesion with side branch \>2.0 mm or side branch which will be recanalised at occlusion due to PCI * Lesion in arterial or venous bypass or anastomosis with coronary * Angiographic contra-indication to IVUS * Severe renal insufficiency (creatinine clearance \<30 mL/') * Severe hepatic insufficiency * Systemic inflammatory pathology of any kind * Uncorrected hyperthyreosis * Hematologic or other malignancy, prior radio- or chemotherapy * Severe peripheral artery disease (accesproblem via groin) * Use of corticosteroïds or immune suppression therapy * Contrastallergy * Life expectancy \<1 year * Participation in other clinical study which has not ended yet