Atherosclerotic cardiovascular disease is the major cause of morbidity and mortality in Western societies. It is a complex genetic disorder with many genes involved and significant gene-environment interactions. The aim of the study is to identify novel genetic- and biological-markers of atherosclerosis. Atherosclerosis is assessed in the coronary arteries using coronary angiography as well as in the carotid artery (intima-media-thickness) and peripheral vessels (ankle brachial index). Association analysis of genetic and metabolic markers with atherosclerotic burden will be performed to identify novel factors of disposition to atherosclerotic vascular disease.
Study Type
OBSERVATIONAL
Enrollment
4,000
University of Leipzig, Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics
Leipzig, Germany
RECRUITINGUniversity of Leipzig, Heart Center, Department of Cardiology
Leipzig, Germany
RECRUITINGThis platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.