RATIONALE: Learning about physical ability and mental function over time in older patients with acute myeloid leukemia may help doctors learn about the long-term effects of treatment and plan the best treatment. PURPOSE: This clinical trial is assessing physical and mental status in older patients with newly diagnosed acute myeloid leukemia.
OBJECTIVES: Primary * Test the feasibility of pre-treatment, bedside assessment of functional and cognitive status in older adults with newly diagnosed acute myeloid leukemia (AML). Secondary * Obtain preliminary data regarding the predictive value of pre-treatment, bedside assessment of functional and cognitive status on overall survival, length of hospitalization and early death. OUTLINE: This is a prospective study. At baseline, patients complete questionnaires including the Vulnerable Elders Survey (functional status), the Mini-Mental Status Exam (cognition), and the Center for Epidemiologic Studies-Depression. Patients also undergo physical function testing via the Short Physical Performance Battery and hand grip strength. Further information parameters are obtained by periodic medical chart reviews. Patients are followed every 3 months for up to 2 years.
Study Type
OBSERVATIONAL
Enrollment
11
Wake Forest University Comprehensive Cancer Center
Winston-Salem, North Carolina, United States
feasibility of administering a functional assessment in clinical situation
Assessment of physical and cognitive function via a set of physical and congnitive tests
Time frame: 72 hours of admission
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