A Study To Test The Interaction of Two Medications for Treatment of Overactive Bladder

Inclusion Criteria: * Healthy adult males \& females ages 18-65; * Body weight \>50kg; BMI between 19-32; * Signed and dated informed consent; QTc Interval \<450 msec; Exclusion Criteria: * Resting blood pressure \>140/90 mmHg or HR \>100 at screening; * History of drug allergy or other allergy which, in the opinion of the PI, contraindicates their participation; * Positive urine drug, alcohol or serum pregnancy test at screening and prior to dosing; * Positive HIV, Hepatitis B, C at screening; use of medications (except acetaminophen)or vitamins or herbal supplements within 7 days or 5 half lives prior to dosing and during study; * history of urinary retention, gastric retention, and other sever gastrointestinal motility conditions, uncontrolled narrow-angle glaucoma or who are at risk for these conditions; * history of chronic constipation and/or regular laxative use; donation of more than 500mL of blood within 56 days prior to dosing; * clinically relevant abnormality identified during screening process or any medical condition or circumstance making the subject unsuitable for participation based on the Investigators assessment