Functional Outcomes Following Limb Sparing Surgery for Sarcoma Patients

M.D. Anderson Cancer Center

Overview

Primary Objectives: 1. To classify the types of wound healing complications that occur after pre-operative radiation therapy and limb sparing resection for the treatment of soft tissue sarcomas of the extremity. 2. To evaluate the impact of each complication type on patient function and quality of life using the Toronto Extremity Salvage Score (TESS).

Study Type

OBSERVATIONAL

Conditions

Sarcoma

Interventions

QuestionnaireBEHAVIORAL

Toronto Extremity Salvage Score (TESS) questionnaire.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Diagnosis of soft tissue sarcoma with histopathologic confirmation. 2. Treatment protocol that includes pre-operative radiation therapy. 3. Treatment protocol that includes limb-sparing surgical resection. 4. Patient has received MD Anderson Cancer Center multidisciplinary care. 5. Patient must be at least three years post-operative. Exclusion Criteria: 1. Previous radiotherapy to the local site. 2. Presence of regional or distant metastases. 3. Major medical co-morbidities (eg. cerebrovascular accident, congestive heart failure, concurrent malignancy) or disabilities unrelated to treatment for soft tissue sarcoma.

Locations (1)

U.T.M.D. Anderson Cancer Center

Houston, Texas, United States

Outcomes

Primary Outcomes

Endpoints for this study will be anatomic site, histological subtype, primary wound closure, wound complication type, need for secondary operation and type of secondary operation.

Time frame: 1 Year

Data from ClinicalTrials.gov

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