The aim of the study is to evaluate the therapeutic efficacy, safety and local tolerability of two different paracetamol-containing solutions in postoperative total hip replacement. They will be compared to placebo (a dummy treatment which contains no active ingredient).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
148
Four 100 mL, 15 min IV infusions at six hour intervals
Four 100 mL, 15 min IV infusions at six hour intervals
Four 100 mL, 15 min IV infusions at six hour intervals
Réthy Pál Kórház-Rendelőintézet
Békéscsaba, Hungary
Semmelweis Egyetem Ortopédiai Klinika
Budapest, Hungary
Esztergom Város Önkormányzat Vaszary Kolos Kórháza
Esztergom, Hungary
Petz Aladár Megyei Oktató Kórház
Győr, Hungary
Amount of PCA-administered morphine consumed during first six hours of study drug treatment
Time frame: 6 hours from first (of four) study drug doses
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Bács-Kiskun Megyei Önkormányzat Kórháza
Kecskemét, Hungary
SZTE ÁOK Ortopédiai Klinika
Szeged, Hungary
Tolna Megyei Önkormányzat Balassa János Kórháza
Szekszárd, Hungary
Fejér Megyei Szent György Kórház
Székesfehérvár, Hungary