The purpose of this study is to evaluate the efficacy of praziquantel versus As+SMP (Co-Arinate FDC ®) in the treatment of Schistosoma haematobium in 6-15 year old Malian children. The nul-hypothesis in this study is that the combination of As+SMP is more effective than praziquantel in the treatment of S. haematobium infected children.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
800
Unnamed facility
Djalakorodji, Mali
Compare the parasite load between the two treatment arms
Time frame: After 28 days
Compare the amount of eggs produced between the two treatment arms
Time frame: After 28 days
Compare cure rate between the two treatment arms
Time frame: After 28 days
Evaluate changes in urine appearance before and after treatment
Time frame: After 28 days
Evaluate changes in haematuria frequency before and after treatment
Time frame: After 28 days
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