Intravenous patient-controlled analgesia (PCA) is a popular technique for postoperative pain management. Although several drugs are recognized as effective therapeutic options, optimal selection of drugs in hysterectomy patients underwent different anesthesia treatments remains unknown explicitly. The investigators hypothesized that butorphanol and tramadol can produce different analgesic effects with intravenous PCA after abdominal hysterectomy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
841
Saline infusion adjunct to morphine PCA pump
Butorphanol was delivered at a continuous infusion manner adjunct to morphine PCA pump
100mg tramadol was used preemptively to morphine PCA pump
Nanjing Maternal and Child Care Hospital
Nanjing, Jiangsu, China
VAS pain scoring;
Time frame: 5 months
VAS sedation scoring; VAS happiness scoring; Adverse effects; Patient's overall conditions.
Time frame: 5 months
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Preemptive saline as a control group to tramadol one