Iron Overload Assesment in Sickle Cell Anemia and Sickle Cell Thalassemia

HaEmek Medical Center, Israel50 enrolled

Overview

Iron overload is well study in Thalassemia patients and it's not only related to blood transfusions, since intestinal iron absorption is also increased in those patients. Sickle cell patients didn't develope significant clinical symptoms and signs of iron overload in spite frequent transfusions. The purpouse of this study is to assess the iron overload in Sickle cell anemia and Sickle cell Thalassemia patients using clinical parameters and cardiac T2\*MRI in order to determine the cardiac and liver iron.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Sickle Cell Anemia Sickle Cell Thalassemia Iron Overload MRI

Interventions

Cardiac and Liver T2* MRIOTHER

Laboratory examinations that are routinely used in follow up of those patients and T2\* MRI analysis.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All the patients with Sickle cell anemia and Sickle cell Thalasemia that are currently in follow up at the Pediatric Hematology Unit Exclusion Criteria: * Age below 18 years.

Locations (1)

Pediatric Hematology Unit and Pediatric Dpt B - HaEmek Medical Center

Afula, Israel

Outcomes

Primary Outcomes

Assessment of Iron overload.

Time frame: December 2008

Secondary Outcomes

Institute the criteria for iron chelator treatment

Time frame: December 2008

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.