A Study for Patients With Complicated Skin and Skin Structure Infections

Inclusion Criteria * Complicated skin and skin structure infection, presumed or proven to be caused by gram-positive pathogen(s). * Patients, ages 18 years and older, must not be below normal body weight or morbidly obese. * Female patients must not be pregnant at time of enrollment and must agree to a reliable method of birth control during the study and for 6 months following the last dose of study drug. Exclusion Criteria: Patients: * with a condition which would prevent performing protocol safety and efficacy assessments. * who have received antibiotics for more than 24 hours within the last 3 days. * with an infection involving deep tissues or unlikely to be caused by gram positive bacteria * who are nursing and will not stop nursing for at least 6 months * with a prior allergic reaction to glycopeptides (e.g. vancomycin) * with any of the following: 1. toxic shock syndrome or toxic-like syndrome 2. presumed or proven infection caused by Clostridium species 3. bone infections 4. ischemic or gangrenous ulcers or wounds 5. infections caused only by gram-negative bacteria 6. infection of an artificial joint that cannot be removed 7. infection of the scrotum, perineum or perianal region 8. infection of a severe burn wound 9. severe ear infection involving bone and/or cartilage 10. infection following injury in water possibly containing Vibrio species or following a history of eating raw oysters within 1 week prior to disease onset