This Phase II, single-arm, open-label, multicenter trial is designed to evaluate the safety, efficacy, and pharmacokinetics of PRO95780 when combined with rituximab in patients with follicular, CD20-positive B-cell NHL that has progressed following previous rituximab therapy.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
49
Objective response, as determined by independent review facility
Time frame: 8 months
Progression-free survival, as determined by independent review facility
Time frame: up to 12 months
Duration of objective response, as determined by independent review facility
Time frame: up to 10.3 months
Overall survival
Time frame: Up to 18.5 months
Objective response, as determined by the investigator
Time frame: Up to 8 months
Progression-free survival, as determined by the investigator
Time frame: Up to 18.5 months
Duration of objective response, as determined by the investigator
Time frame: Up to 14.1 months
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