Endoscopic Ultrasound (EUS) Guided Treatment With Humira for Crohn's Perianal Fistulas

Inclusion Criteria: A patient may be considered for study participation if all of the following apply: * Male and Female aged 18 years or older; and * A confirmed diagnosis of Crohn's disease and one or more identifiable perianal fistulas. Exclusion Criteria: A patient will be excluded from the study if one or more of the following apply: * Females who are pregnant or breast feeding; * Infliximab received within 6 weeks prior to study entry; * Patients who cannot take, or refuse to take concomitant immunosuppressive therapy with either azathioprine, 6-mercaptopurine, or methotrexate; Unless patient has been intolerant of these therapies in the past or is contraindicated as determined by the investigator; * Patients who cannot take, or refuse to take concomitant antibiotic therapy; * Patients with severe anal stenosis or tenderness which would preclude colonoscopy and / or rectal EUS; * Patients who cannot take or refuse to take adalimumab; * Patients with active or latent tuberculosis; * Patients who have had systemic antibiotic, antiviral or antifungal treatment(s) within 3 weeks prior to Screening for all non-Crohn's related infections; * Patients concurrently taking anakinra (Kineret); * Patients with a history of cancer or lymphoproliferative disease other than a successfully and completely treated cutaneous squamous cell or basal cell carcinoma or carcinoma in-situ of the cervix; * Patients with chronic hematologic problems such as bleeding dyscrasias; * Patients with a history of demyelinating disease (i.e. multiple sclerosis); and * Patients with congestive heart failure.